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leprae. Anin silicostudy was carried out to comprehend the molecular interactions amongst DNA gyrase and WQ compounds. WQ-3334 and WQ-3810 had been revealed to acquire increased inhibitory activity againstM. lepraeDNA gyrase than Many others. On top of that, Examination utilizing quinolone-resistantM. lepraeDNA gyrases confirmed that WQ-3334 had gr